Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Obvious+ tissue clearing procedure is the only real method that delipidates samples without any adjust in morphology and with negligible impact on structural integrity.
Megatome is actually a vibrating microtome intended to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface area profile, and also small tissue problems and knowledge decline.
Antibodies may just take weeks to diffuse by only a few millimeters of tissue, having a steep labeling gradient from surface area to core.
Megatome is designed for accuracy: the blade vibrates at the next frequency and bigger amplitude array than other microtomes, and features a special deflection Management mechanism.
SE employs a rotational electrical discipline to disperse remarkably electromobile molecules (like antibodies or surfactant micelles) all over a porous sample devoid of damaging electrically billed constructions throughout the tissue. This enables 2-4 day clearing of intact organs,
Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them totally clear. This enables light-weight penetration into the sample and makes certain the acquisition of high-resolution, in-target graphic data.
Megatome is actually a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and knowledge reduction.
eFLASH is a swift tissue labeling approach which allows for uniform complete-organ staining in 20 rounds of labeling.
Entirely delipidate total mouse brains or comparably sized samples in only one working day with SmartBatch+, or in one week with our passive clearing package.
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Leverage the Apparent+ tissue clearing strategy, as well as eFLASH and patented stochastic electrotransport technologies, to rapidly crystal clear and label complete organs. Critical highlights and attributes involve:
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